The Biochemistry of Fermentation: Unlocking the Potency of Hadasei-3™

Update on Jan. 6, 2026, 5:52 p.m.

In the ancient beauty rituals of Japan, ingredients were rarely used in their raw, unprocessed state. They were soaked, brewed, and fermented. This wasn’t just culinary tradition spilling over into vanity; it was an early, intuitive application of biotechnology. Today, modern science validates what geishas understood empirically: that fermentation transforms simple botanicals into potent bio-actives.

TATCHA The Dewy Skin Cream is built upon this principle. Its core, the Hadasei-3™ complex, is a product of double-fermenting three superfoods: Uji Green Tea, Akita Rice, and Okinawa Algae. But what exactly happens in the fermentation vat? Why is a fermented leaf better for your skin than a fresh one? This article deconstructs the biochemistry of fermentation, exploring how microbial enzymes break down cell walls, reduce molecular weight, and create entirely new compounds that the skin can actually use.

The Enzymatic Key: Breaking the Cellular Lock

Raw plant materials are locked vaults. The beneficial nutrients—polyphenols, vitamins, amino acids—are trapped inside rigid cell walls made of cellulose and lignin. The human skin does not possess the enzymes (like cellulase) necessary to break down these walls efficiently. Applying raw plant extract often means the nutrients sit on the surface, unable to penetrate.

The Role of Microbes

Fermentation introduces a biological key: Microbes (yeast or bacteria). * Enzymatic Hydrolysis: During fermentation, these microbes secrete enzymes that digest the tough plant cell walls. This process, known as enzymatic hydrolysis, liberates the intracellular nutrients, making them available. * Molecular Fragmentation: More importantly, the enzymes chop long-chain molecules (proteins, polysaccharides) into smaller fragments (peptides, simple sugars). * Bioavailability: In dermatology, size matters. The 500 Dalton Rule suggests that molecules larger than 500 Daltons struggle to penetrate the skin barrier. Fermentation reduces the molecular weight of the ingredients, significantly enhancing their Bioavailability. The Hadasei-3™ complex is essentially “pre-digested” nutrition, engineered by nature to bypass the skin’s gatekeepers and deliver benefits deeper into the epidermis.

TATCHA The Dewy Skin Cream

The Trinity of Hadasei-3™: A Phytochemical Analysis

The specific choice of Green Tea, Rice, and Algae is not arbitrary. Each undergoes a specific transformation during fermentation.

1. Uji Green Tea: The Detoxifier

Green tea is rich in Epigallocatechin Gallate (EGCG), a potent antioxidant. * Fermentation Effect: Fermentation stabilizes these catechins and can produce new compounds like theaflavins. These compounds are known to reduce oxidative stress and inhibit the enzymes (like collagenase) that break down collagen. In the fermented state, they are more stable and less prone to oxidation before they reach the skin.

2. Akita Rice: The Nourisher

Rice water has been a beauty staple for centuries. It is rich in starch and proteins. * Fermentation Effect: When rice ferments (think sake production), the proteins are broken down into Amino Acids and Peptides. It also produces Kojic Acid, a byproduct known for inhibiting tyrosinase (the enzyme that produces melanin), leading to a brighter complexion. The lactic acid produced during fermentation acts as a gentle alpha-hydroxy acid (AHA), promoting cell turnover and hydration without irritation.

3. Okinawa Algae: The Hydrator

Algae is a survivor, thriving in harsh saline environments. It creates polysaccharides to retain water. * Fermentation Effect: Fermenting algae breaks these polysaccharides down into smaller sugar units that act as powerful Humectants. They bind water to the skin surface. Furthermore, algae is rich in minerals (magnesium, zinc). Fermentation chelates these minerals, binding them to organic molecules, which increases their absorption and utilization by skin cells.

The Creation of Postbiotics

Fermentation does more than just break things down; it creates new things. The resulting broth contains Postbiotics. * Metabolic Byproducts: These include short-chain fatty acids (SCFAs), enzymes, and antimicrobial peptides produced by the fermenting microbes. * Acid Mantle Support: These postbiotics help regulate the skin’s pH, maintaining the Acid Mantle (pH 4.5-5.5). A healthy acid mantle is crucial for barrier function and for keeping pathogenic bacteria (like P. acnes) in check. By applying a fermented product like The Dewy Skin Cream, you are essentially inoculating the skin with a supportive chemical environment that favors a healthy microbiome.

TATCHA The Dewy Skin Cream

The Physics of “Dewy”: Refractive Index and Hydration

The product promises a “dewy glow.” This is not just marketing; it is physics. * Hydration and Transparency: Well-hydrated skin cells (corneocytes) swell and lie flat. This reduces light scattering and increases light transmission. * Refractive Index: The fermentation-derived humectants (like lactic acid and amino acids) increase the water content of the Stratum Corneum. Water has a refractive index distinct from dry protein. By optimizing the water gradient in the skin, the cream alters how light interacts with the surface, creating a “specular reflection” (shine) rather than a “diffuse reflection” (dullness). This is the scientific basis of the “dewy” look—it is the optical signature of cellular hydration.

Conclusion: Ancient Wisdom, Molecular Proof

TATCHA The Dewy Skin Cream is a testament to the fact that tradition and science are not opposing forces. The ancient practice of fermentation is, in reality, a sophisticated biological processing method.

By utilizing the Hadasei-3™ complex, Tatcha leverages microbial enzymes to perform molecular surgery on plant ingredients, enhancing their penetration, potency, and compatibility with human skin. It transforms food-grade ingredients into high-performance cosmeceuticals. For the user, this means that the luxury price tag is paying for a product that is biologically optimized to work with the skin’s metabolic processes, delivering nutrition in a form the body recognizes and welcomes.